Blog

Blog

Welcome to the RCONIS blog!

Two Minutes at the Eclipse Splash Screen: A Copilot Module on Repeat

How a small terminal module triggered a big plugin dependency search
engineering
Eclipse
Windows
Copilot
Troubleshooting

Diagnosing repeated Eclipse startup delays with Java thread dumps, and a tested workaround that reduced the wait from two minutes to four seconds.

Oct 27, 2026
Friedrich Pahlke

crmPack 2.1: Backfill cohort simulations

package
statistics
This release marks yet another major update of the crmPack package: Backfill cohort simulations are now supported in the Design class, powered by the new Backfill class.…
Feb 12, 2026
Daniel

Our paper on the statistical open-source software revolution in pharma

paper
software
We are excited to announce the open-access publication of our new paper “The statistical software revolution in pharmaceutical development: challenges and opportunities in…
Feb 5, 2026
Daniel

RobinCar2: Reliable Covariate Adjustment Package

package
statistics
Covariate adjustment has been a hot topic now for a while in clinical trial statistics. Personally I witnessed this first hand at the Regulatory Industry Statistics Workshop…
Jan 14, 2026
Daniel

crmPack 2.0: A Major Milestone for Adaptive Dose Escalation Trials

package
statistics
Adaptive dose escalation trials are a key tool for Phase 1 development both in oncology and non-oncology settings. The R package crmPack has been developed over the last 11…
Dec 1, 2025
Daniel

RCONIS at ISCB 2025

conference
Daniel describes here his highlights from the ISCB 2025 conference in Basel, Switzerland, which took place 24-28 August 2025.
Oct 8, 2025
Daniel

RCONIS has its first birthday!

engineering
statistics

We show you what we have been busy with in this first year.

Jul 15, 2025
Daniel and Friedrich

Troubleshooting Eclipse StatET RMI Registry Port Errors on Windows

engineering
R
Eclipse
StatET

How to resolve the RMI registry port error ‘RMI Registry at port 51199 could not be started’ in Eclipse with StatET on Windows.

Jun 17, 2025
Friedrich Pahlke

RCONIS at PharmaSUG Single-Day Event Japan 2025

conference
The Pharma Software Users Group (SUG) Japan held a Single-Day Event (SDE) in Tokyo on 7 April 2025. This was the first face-to-face event since the pandemic, and took place…
Apr 16, 2025
Daniel

RCONIS at China Pharma R User Group (RUG) Meeting 2025

conference
The 3rd China Pharmaceutical Industry R User Group (RUG) Meeting was held on March 28, 2025, both on-site and online. On-site meeting locations were Shanghai (Johnson &…
Apr 12, 2025
Daniel

Debugging memory issues in compiled code in R packages

engineering
R
C++
This is the story of a long lasting issue we had in the mmrm package, and how we solved it together with the open source community. Along the way, we learned a lot about…
Feb 24, 2025
Daniel

Minimal Detectable Difference (MDD) vs. Target Effect Size

statistics
R
Maybe you have heard about the “Minimum Detectable Difference” (MDD) and the “Target Effect Size” in the context of clinical trials. These two concepts are crucial for the…
Feb 7, 2025
Daniel

First R Base Contribution

engineering
R
Excited about our first RCONIS contribution to R Base Code! 🚀
Aug 10, 2024
Daniel
No matching items